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Terms to Know

Since you are going to be speaking with healthcare professionals, it will help to be familiar with some of the terms they may use. The list below contains some of the common terms you should know.

Choose a category—Symptoms,* Behaviors, and Feelings , Treatments/Medications , General Terms —or simply scroll through the list.

 
 

Symptoms,* Behaviors, and Feelings:

Active listening: A way of listening in which a person shows interest in what another person is saying and shows that he or she understands the other person’s point of view

Affective flattening: This is when a person doesn't have an emotional response, or has an inappropriate response, to what's going on around him or her

Agitated: Feeling restless and anxious

Alogia: Not talking a lot, and not being able to think clearly. It's when someone has difficulty speaking with others or sometimes just gives short answers

Avolition: This is when a person doesn't feel like doing anything at all. A person may sit for long periods of time and show little interest in participating in work or everyday activities, like bathing or getting dressed

Catatonic behavior: Not being active in any way at all, as if in a stupor or a trance. May appear as one of the positive symptoms of schizophrenia

Delusions: Strongly believing in ideas that are false; for example, believing that a light bulb is sending secret messages or that the FBI can read one’s thoughts. May appear as one of the positive symptoms of schizophrenia

Approved for the treatment of schizophrenia.

✶Please discuss your symptoms with your healthcare professional. He or she will review your symptoms and may consult the established guidelines, which are available in the Diagnostic and Statistical Manual of Mental Disorders, where applicable.

 

Disorganized behavior: Behaving in a way that seems unpredictable or silly to onlookers. May appear as one of the positive symptoms of schizophrenia

Disorganized speech: Ongoing, rambling speech that does not make any sense. May appear as one of the positive symptoms of schizophrenia

Hallucinations: Hearing, seeing, feeling, tasting, or smelling something that other people aren't experiencing. The most common hallucinations are those that affect hearing, such as hearing imaginary voices. A person with schizophrenia may be seen talking to imaginary people. May appear as one of the positive symptoms of schizophrenia

Impulsive: Doing something without thinking about it first

Negative symptoms: A lack of behaviors or feelings that are normally present, such as losing interest in everyday activities, feeling out of touch with people, lack of feelings and emotions, having less ability to experience pleasure

Positive symptoms: Extra feelings or behaviors that are usually not present, such as seeing, feeling, hearing, or tasting things that other people aren't experiencing; believing things that are not true or real; exhibiting disorganized speech and behavior

Psychotic episode: An often sudden appearance of symptoms during which a person is not able to tell the difference between what is real and unreal. Contact a doctor for more information

Sensory overload: When too much is happening at once around a person, causing him or her to feel overwhelmed

Approved for the treatment of schizophrenia.✶Please discuss your symptoms with your healthcare professional. He or she will review your symptoms and may consult the established guidelines, which are available in the Diagnostic and Statistical Manual of Mental Disorders, where applicable.

 

 

Treatments/Medications:

Atypical antipsychotic: A class of drugs developed and first used in the 1990s that can help control the symptoms of schizophrenia

Long-acting antipsychotic injectable medication: A type of medication that is released slowly in the body, allowing the medicine to work for weeks at a time. As a result, the medicine does not need to be taken every day

Oral medication: A type of medication taken by mouth that comes in a variety of forms, including tablet, capsule, and liquid forms

Typical (or first generation) antipsychotic: This class of drug has been used for over 50 years to help control the symptoms of schizophrenia

 

General Terms:

Caregivers: People who take care of a family member or friend in need of help

Healthcare professional: Someone who is professionally trained to treat people with schizophrenia and/or other diseases

Motivation: A person’s real reason for doing or saying something

Peer support: A group of other individuals with schizophrenia or a group made of people who care for people with schizophrenia. They meet to socialize and support each other because they have a better understanding of what each other is going through

Personal hygiene (self-care): Keeping your body clean, including taking showers, grooming hair, and brushing teeth

Recovery process: An ongoing personal process of working to achieve your goals even though you have an illness

Relapse: When the symptoms of schizophrenia come back or worsen after a person in treatment has been feeling and appears to be getting better for a period of time

Schizophrenia: A mental illness that can affect a person's ability to think clearly, manage feelings, make decisions, and relate to others. The condition has no cure, but can be manageable

Self-care (personal hygiene): Attention to personal grooming, such as brushing or combing hair, bathing, and getting dressed

Treatment plan: A comprehensive medical care plan for an illness that can include medication, therapy, and support

INDICATION

INDICATION

INVEGA TRINZA® (3-month paliperidone palmitate) is a prescription medicine given by injection every 3 months by a healthcare professional and used to treat schizophrenia. INVEGA TRINZA® is used in people who have been treated with INVEGA SUSTENNA® (1-month paliperidone palmitate) for at least 4 months.

INVEGA SUSTENNA® (In-VEY-guh Suss-TEN-uh) (paliperidone palmitate) is a prescription medicine given by injection by a healthcare professional. INVEGA SUSTENNA® is used to treat schizophrenia in adults. 

 

IMPORTANT SAFETY INFORMATION

IMPORTANT SAFETY INFORMATION
What is the most important information I should know about INVEGA TRINZA® and INVEGA SUSTENNA®?
INVEGA TRINZA® and INVEGA SUSTENNA® can cause serious side effects, including an increased risk of death in elderly people who are confused, have memory loss, and have lost touch with reality (dementia-related psychosis). INVEGA TRINZA® and INVEGA SUSTENNA® are not for treating dementia-related psychosis.

Do not receive INVEGA TRINZA® or INVEGA SUSTENNA® if you are allergic to paliperidone, paliperidone palmitate, risperidone, or any of the ingredients in INVEGA TRINZA® or INVEGA SUSTENNA® . See the end of the Patient Information leaflet in the full Prescribing Information for a complete list of INVEGA TRINZA® and INVEGA SUSTENNA® ingredients.

Before you receive INVEGA TRINZA®  or INVEGA SUSTENNA®, tell your healthcare professional about all your medical conditions, including if you:

  • have had Neuroleptic Malignant Syndrome (NMS)
  • have or have had heart problems, including a heart attack, heart failure, abnormal heart rhythm, or long QT syndrome
  • have or have had low levels of potassium or magnesium in your blood
  • have or have had uncontrolled movements of your tongue, face, mouth, or jaw (tardive dyskinesia)
  • have or have had kidney or liver problems
  • have diabetes or have a family history of diabetes
  • have had a low white blood cell count
  • have had problems with dizziness or fainting or are being treated for high blood pressure
  • have or have had seizures or epilepsy
  • have any other medical conditions
  • are pregnant or plan to become pregnant. It is not known if INVEGA TRINZA® or INVEGA SUSTENNA® will harm your unborn baby
    • If you become pregnant while taking INVEGA TRINZA®  or INVEGA SUSTENNA®, talk to your healthcare professional about registering with the National Pregnancy Registry for Atypical Antipsychotics. You can register by calling 1-866-961-2388 or visit http://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry.
    • Infants born to women who are treated with INVEGA TRINZA® or INVEGA SUSTENNA® may experience symptoms such as tremors, irritability, excessive sleepiness, eye twitching, muscle spasms, decreased appetite, difficulty breathing, or abnormal movement of arms and legs. Let your healthcare professional know if these symptoms occur.
  • are breastfeeding or plan to breastfeed. INVEGA TRINZA® and INVEGA SUSTENNA® can pass into your breast milk. Talk to your healthcare professional about the best way to feed your baby if you receive INVEGA TRINZA® or INVEGA SUSTENNA®.

Tell your healthcare professional about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Know the medicines you take. Keep a list of them to show to your healthcare professional or pharmacist when you get a new medicine.

Patients (particularly the elderly) taking antipsychotics with certain health conditions or those on long-term therapy should be evaluated by their healthcare professional for the potential risk of falls.

What should I avoid while receiving INVEGA TRINZA® or INVEGA SUSTENNA®?

  • INVEGA TRINZA® and INVEGA SUSTENNA® may affect your ability to make decisions, think clearly, or react quickly. Do not drive, operate heavy machinery, or do other dangerous activities until you know how INVEGA TRINZA® or INVEGA SUSTENNA® affects you.
  • avoid getting overheated or dehydrated.

INVEGA TRINZA® and INVEGA SUSTENNA® may cause serious side effects, including:

  • See “What is the most important information I should know about INVEGA TRINZA® and INVEGA SUSTENNA®?”
  • stroke in elderly people (cerebrovascular problems) that can lead to death
  • Neuroleptic Malignant Syndrome (NMS). NMS is a rare but very serious problem that can happen in people who receive INVEGA TRINZA® or INVEGA SUSTENNA®. NMS can cause death and must be treated in a hospital. Call your healthcare professional right away if you become severely ill and have any of these symptoms: high fever; severe muscle stiffness; confusion; loss of consciousness; changes in your breathing, heartbeat, and blood pressure
  • problems with your heartbeat. These heart problems can cause death. Call your healthcare professional right away if you have any of these symptoms: passing out or feeling like you will pass out, dizziness, or feeling as if your heart is pounding or missing beats
  • uncontrolled movements of your tongue, face, mouth, or jaw (tardive dyskinesia)
  • metabolic changes. Metabolic changes may include high blood sugar (hyperglycemia), diabetes mellitus and changes in the fat levels in your blood (dyslipidemia), and weight gain
  • low blood pressure and fainting
  • changes in your blood cell counts
  • high level of prolactin in your blood (hyperprolactinemia). INVEGA TRINZA® or INVEGA SUSTENNA® may cause a rise in the blood levels of a hormone called prolactin (hyperprolactinemia) that may cause side effects including missed menstrual periods, leakage of milk from the breasts, development of breasts in men, or problems with erection
  • problems thinking clearly and moving your body
  • seizures
  • difficulty swallowing that can cause food or liquid to get into your lungs
  • prolonged or painful erection lasting more than 4 hours. Call your healthcare professional or go to your nearest emergency room right away if you have an erection that lasts more than 4 hours
  • problems with control of your body temperature, especially when you exercise a lot or spend time doing things that make you warm. It is important for you to drink water to avoid dehydration

The most common side effects of INVEGA TRINZA®  include: injection site reactions, weight gain, headache, upper respiratory tract infections, feeling restlessness or difficulty sitting still, slow movements, tremors, stiffness and shuffling walk.

The most common side effects of INVEGA SUSTENNA® include: injection site reactions; sleepiness or drowsiness; dizziness; feeling of inner restlessness or needing to be constantly moving; abnormal muscle movements, including tremor (shaking), shuffling, uncontrolled involuntary movements, and abnormal movements of your eyes.

Tell your healthcare professional if you have any side effect that bothers you or does not go away. These are not all the possible side effects of INVEGA TRINZA® or INVEGA SUSTENNA®. For more information, ask your healthcare professional or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects of prescription drugs to the FDA at 1‑800‑FDA‑1088.

General information about the safe and effective use of INVEGA TRINZA® or INVEGA SUSTENNA®

Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. Do not use INVEGA TRINZA® or INVEGA SUSTENNA® for a condition for which it was not prescribed. Do not give INVEGA TRINZA® or INVEGA SUSTENNA® to other people, even if they have the same symptoms that you have. It may harm them. You can ask your pharmacist or healthcare professional for information about INVEGA TRINZA® or INVEGA SUSTENNA® that is written for healthcare professionals.

This Patient Information leaflet summarizes the most important information about INVEGA TRINZA® and INVEGA SUSTENNA® . If you would like more information, talk with your healthcare professional.

You can ask your healthcare professional or pharmacist for more information that is written for healthcare professionals. For more information, go to www.invegatrinza.com or www.invegasustenna.com or call 1‑800‑526‑7736.

Please click to read the full Prescribing Information, for INVEGA TRINZA® and INVEGA SUSTENNA® and discuss any questions you have with your healthcare professional.

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